Alzheimer's Disease Genetics Study
The purpose of the Alzheimer’s Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer’s Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying and collecting genetic material from families with multiple members diagnosed with AD or dementia.
Description
The purpose of the Alzheimer’s Disease Genetics Study is to help identify the genes that may be responsible for causing Alzheimer’s Disease (AD) by collecting genetic material from families with multiple members diagnosed with AD. Qualifying families will have two living blood-related individuals who have been diagnosed with or are showing symptoms of AD or dementia. Local study sites are located all over the United States, and arrangements may be made for eligible families who do not live near a participating site. The biological samples and data from these families will be made available to qualified researchers, who must sign a Materials Transfer Agreement (MTA) in order to protect the privacy rights of study participants before receiving DNA and data.
Status: Recruiting (N/A). Started on June 1st, 2002.
Enrollment: 3000 subjects
Study Type: Observational
Study Design:
- Observational Model: Cohort
- Time Perspective: Prospective
Conditions:
Interventions:
Eligibility
Inclusion Criteria:
Two living family members diagnosed with AD or other dementia with any age of onset
Biological samples available
Fresh blood, or
Immortalized lymphoblastic cell lines, or
3-5 grams of frozen cerebral cortex; fixed samples are not accepted
Please note: this study does not include genetic counseling; because no personal identifying information such as name or date of birth is attached to samples, results of individual tests are not available to participants or family members.
Exclusion Criteria:
Does not meet inclusion criteria
Member of a family that was included in the National Institute of Mental Health AD Genetics Sib Pair collection
- Gender
Both
- Mininum Age
N/A
- Maximum Age
N/A
- Healthy Volunteers
Accepts Healthy Volunteers
Resources
Source: Indiana University
Authority: United States: Federal Government
Locations
-
Participants are being recruited from all over the United States
Nationwide
Indiana
United States
Officials
Tatiana M. Foroud, PhD (Principal Investigator, National Cell Repository for Alzheimer's Disease (NCRAD), Indiana University)
Sponsors
Indiana University (Lead Sponsor)
National Institute on Aging (NIA) (Collaborator)
References
None.
Links
- Date Verified
- October 1st, 2010
- First Received
- October 18th, 2010
- Last Changed
- October 18th, 2010
Information obtained from ClinicalTrials.gov on June 09, 2011. Link to the current ClinicalTrials.gov record.
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