Influence of Soy Consumption on Menopause
The purpose of this study is to examine the way soy consumption affects menopausal symptoms in middle-aged Japanese women.
Description
For the past 20 years, Japanese women have reported fewer menopausal symptoms than their North American counterparts. One explanation for the disparity is the differences in diet. Evidence suggests that Japanese women consume large amounts of soy, a phytoestrogen that is structurally similar to the hormone estrogen. However, there is a lack of menopause-related research data from non-Western populations. This study will be a long-term observation of the effects of soy consumption in menopausal Japanese women.
This study will last 6 months. Participants will complete a dietary log and a menopausal symptom checklist daily. There will be three or four study visits. During these visits, participants will complete a diet questionnaire, have a blood sample collected, and be interviewed about their menopausal symptoms. Six months after study completion, participants will be sent a questionnaire about any recent menopausal symptoms they may have experienced.
Status: Completed (N/A). Started on November 1st, 2001. Ended on August 1st, 2003.
Enrollment: 120 subjects
Study Type: Observational
Study Design:
- Natural History
- Longitudinal
- Defined Population
- Prospective Study
Conditions:
Interventions:
Eligibility
Inclusion Criteria:
Japanese resident
Menopausal
Exclusion Criteria:
Hysterectomy, removal of ovaries, or tubal ligation with subsequent menstrual changes
Hormones for menopause or birth control pills within 5 years of study entry
Recent major illness
Medication that could affect naturally-produced hormones
- Gender
Female
- Mininum Age
45 Years
- Maximum Age
55 Years
- Healthy Volunteers
Accepts Healthy Volunteers
Resources
Source: National Center for Complementary and Alternative Medicine (NCCAM)
Authority: United States: Federal Government
Locations
-
Loma Linda Clinic
Koriyama
Fukushima
963-8002
Japan
-
Kyoto Prefectural University of Medicine
Kamigyo-ku
Kyoto
602-8566
Japan
Officials
Melissa K. Melby, MPhil, MA (Principal Investigator, Emory University)
Sponsors
National Center for Complementary and Alternative Medicine (NCCAM) (Lead Sponsor)
References
None.
Links
None.
- Date Verified
- January 1st, 2005
- First Received
- August 17th, 2006
- Last Changed
- August 17th, 2006
Information obtained from ClinicalTrials.gov on July 15, 2008. Link to the current ClinicalTrials.gov record.
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