Study on Male Osteoporosis and Aging
The aim of this study is to identify potential risk factors for fragility fractures in men.
Description
Osteoporosis is a disease characterized by decreased bone mass and pathological changes in the microarchitecture of the bones. The clinical significance of osteoporosis is the association with fragility fractures and, consequently, increases in both morbidity and mortality.
In men, genetical and life-style factors are known to affect the risk of fractures, however, data relating these factors with measures of bone mineral density and fracture risk are limited.
30.000 men aged 60-70 were randomly selected from the Central Office of Civil Registration in Denmark. Each receive a questionnaire addressing demographics, potential risk factors of osteoporosis, past medical history and medication by mail. In case of consent, the participants will complete a full medical examination including DXA and sampling of DNA if they have a fragility fracture. At the same time, 2 participants from the study population will be selected as control. The study period is 10 years.
Status: Recruiting (N/A). Started on December 1st, 2006. Ended on December 1st, 2017.
Enrollment: 30000 subjects
Study Type: Observational
Study Design:
- Natural History
- Longitudinal
- Random Sample
- Prospective Study
Conditions:
Interventions:
Eligibility
Inclusion Criteria:
- Men aged 60-70 being able to consent in writing
- Gender
Male
- Mininum Age
60 Years
- Maximum Age
70 Years
- Healthy Volunteers
Accepts Healthy Volunteers
Resources
Source: Odense University Hospital
Authority: Denmark: National Board of Health
Locations
-
Department of Endocrinology
Odense
5000
Denmark
Officials
Kim T Brixen, MD. Ph.d (Principal Investigator, Odense University Hospital)
Sponsors
Odense University Hospital (Lead Sponsor)
Novo Nordisk (Collaborator)
AP Moeller Foundation (Collaborator)
References
None.
Links
None.
- Date Verified
- December 1st, 2006
- First Received
- April 19th, 2007
- Last Changed
- April 19th, 2007
Information obtained from ClinicalTrials.gov on July 15, 2008. Link to the current ClinicalTrials.gov record.
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